In this study, we assessed the efficacy and safety of four skin care products indicated\nfor skin hydration (Aqua Therapy and Perfecta), skin aging (Unica\nResurfacing Therapy) and sensitive skin (Comfort Therapy), in four groups\nof 7 volunteers with different skin types. These products belong to four skin\ncare ranges (Aqua, Perfecta, Unica and Comfort) and are formulated with\na specific combination of active compounds (Dermo28). Evaluation of sebum\nsecretion, hydration and pH of the skin (all groups), wrinkle severity (Unica\nResurfacing Therapy) and erythema (Comfort Therapy) was performed at\nbaseline and after 4 weeks of treatment. A significant increase in hydration\nwas recorded in subjects with dry skin receiving Aqua Therapy for facial hydration\nand Perfecta for body hydration, respectively (p < 0.001 for both). A\nsignificant decrease in the modified Fitzpatrick wrinkle scale (p = 0.006) and\nan increase in sebum secretion and hydration (p = 0.013 and p < 0.001, respectively)\nwere observed in the Unica Resurfacing Therapy group. In subjects\nwith sensitive skin (Comfort Therapy), a decrease in erythema (p =\n0.012), an increase in sebum secretion (p = 0.001) and hydration (p < 0.001),\nand a reduction in pH (p = 0.005) were detected at the end of treatment. Only\none patient reported a minor adverse event. This specific combination of active\ningredients was clinically effective and safe, and contributed to skin surface\nhydrolipidic film regeneration, improvement of wrinkle depth and reduction\nof redness.
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